Breaking the Mold: A Review of Mucormycosis and Current Pharmacological Treatment Options

Tuesday, June 14, 2016 10:00:00 PM

Annals of Pharmacotherapy: Invasive fungal infections are relatively rare because the human immune system efficiently eliminates the large pathogens. However, with advances in modern medicine, more individuals are susceptible to invasive fungal infections resulting from either immunosuppressive disease or immunosuppressive therapy. Treatment of invasive fungal infections is complicated because the drug target sites of eukaryotic pathogens closely resemble those of the human host, which limits therapeutic options. Mucormycosis is a rare invasive fungal infection with exceedingly high mortality and few therapeutic options. The purpose of this review is to highlight the epidemiology, pathophysiology, clinical manifestations, diagnosis, and treatment of invasive mucormycosis...

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